GLP-1 receptor agonists are a class of medications originally developed to help manage type 2 diabetes and are now widely used for medical weight loss. These medications mimic the action of the natural hormone GLP-1 (glucagon-like peptide-1), which helps regulate blood sugar, slow gastric emptying, and reduce appetite. By enhancing feelings of fullness and decreasing food intake, GLP-1 receptor agonists support sustainable weight loss. Common examples include semaglutide and tirzepatide. They are typically administered as weekly injections under medical supervision.